| Rd.Pick | Team | Draftee |
| 1.1 |  San Francisco 49ers | LB DeMarcus Ware |
| 1.2 |  Pittsburgh Steelers | DB Nick Collins |
| 1.3 |  Dallas Cowboys (thru WAS.) | RB Frank Gore |
| 1.4 |  Miami Dolphins | QB Aaron Rodgers |
| 1.5 |  Cleveland Browns | DB Antrel Rolle |
| 1.6 |  Philadelphia Eagles | WR Roddy White |
| 1.7 |  Buffalo Bills | LB Shawne Merriman |
| 1.8 |  Kansas City Chiefs (thru TEN. thru ARZ.) | RB Brandon Jacobs |
| 1.9 |  Seattle Seahawks (thru K.C. thru WAS. thru DAL.) | DB Kerry Rhodes |
| 1.10 |  Los Angeles Raiders | LB Lofa Tatupu |
| 1.11 |  Tennessee Titans (thru SEA. thru K.C.) | DB Oshiomogho Atogwe |
| 1.12 |  San Diego Chargers (thru DET. thru K.C. thru DEN.) | LB Derrick Johnson |
| 1.13 | San Diego Chargers (thru GIA. thru S.D.) | DB Ellis Hobbs |
| 1.14 |  New Orleans Saints | TE Heath Miller |
| 1.15 |  Cincinnati Bengals | LB Kirk Morrison |
| 1.16 |  New York Jets | WR Braylon Edwards |
| 1.17 | Pittsburgh Steelers (thru DET.) | RB Cedric Benson |
| 1.18 | San Diego Chargers (thru GIA. thru S.D. thru GIA.) | QB Kyle Orton |
| 1.19 |  Detroit Lions (thru SEA.) | RB Ryan Grant |
| 1.20 | San Francisco 49ers (thru TEN.) | QB Matt Cassel |
| 2.1 | Miami Dolphins | OL Logan Mankins |
| 2.2 | Cincinnati Bengals (thru ARZ.) | LB Barrett Ruud |
| 2.3 | San Francisco 49ers | DB Chris Harris |
| 2.4 | Kansas City Chiefs (thru K.C. thru DET. thru PIT.) | OL Michael Roos |
| 2.5 | Cleveland Browns | WR Vincent Jackson |
| 2.6 | Seattle Seahawks (thru DET. thru K.C. thru WAS.) | LB Michael Boley |
| 2.7 | Dallas Cowboys | DB Pacman Jones |
| 2.8 | Buffalo Bills | QB Alex Smith |
| 2.9 | Kansas City Chiefs (thru RAI. thru K.C.) | OL Jammal Brown |
| 2.10 | Philadelphia Eagles | DL Jay Ratliff |
| 2.11 |  Arizona Cardinals (thru K.C. thru RAI.) | DB Carlos Rogers |
| 2.12 |  Denver Broncos | LB Odell Thurman |
| 2.13 | Detroit Lions (thru K.C. thru DET. thru S.D.) | DB Brodney Pool |
| 2.14 | San Diego Chargers (thru DET. thru N.O.) | DB Darrent Williams |
| 2.15 | Pittsburgh Steelers (thru CIN.) | DB Bryant McFadden |
| 2.16 | New York Jets | RB Marion Barber |
| 2.17 | Seattle Seahawks (thru DET.) | DL Justin Tuck |
| 2.18 | Denver Broncos (thru RAI. thru GIA.) | DB Justin Miller |
| 2.19 | Seattle Seahawks | RB Ronnie Brown |
| 2.20 | Tennessee Titans | RB Cadillac Williams |
| 3.1 | Detroit Lions (thru MIA.) | QB Jason Campbell |
| 3.2 | Detroit Lions (thru ARZ.) | WR Nate Washington |
| 3.3 | San Francisco 49ers | K Robbie Gould |
| 3.4 | Pittsburgh Steelers | DB Corey Webster |
| 3.5 | Cleveland Browns | QB Derek Anderson |
| 3.6 |  Washington Redskins | LB Cameron Wake |
| 3.7 | Dallas Cowboys | OL Chris Spencer |
| 3.8 | Buffalo Bills | RB Leonard Weaver |
| 3.9 | Tennessee Titans (thru K.C. thru DET. thru K.C.) | LB Heath Farwell |
| 3.10 | Philadelphia Eagles | OL Alex Barron |
| 3.11 | Denver Broncos (thru RAI.) | WR Mark J. Clayton |
| 3.12 | Seattle Seahawks (thru DET. thru DEN.) | LB Thomas Davis |
| 3.13 | Detroit Lions (thru S.D.) | LB Channing Crowder |
| 3.14 | New Orleans Saints | DL Trent Cole |
| 3.15 | Cincinnati Bengals | WR Lance Moore |
| 3.16 | New York Jets | DB Jim Leonhard |
| 3.17 | Detroit Lions | OL Jason Brown |
| 3.18 | Detroit Lions (thru GIA. thru DET. thru GIA.) | DB Gerald Sensabaugh |
| 3.19 | Seattle Seahawks | OL David Stewart |
| 3.20 | Denver Broncos (thru RAI. thru K.C. thru TEN.) | OL Todd Herremans |
| 4.1 | Miami Dolphins | WR Roscoe Parrish |
| 4.2 | Arizona Cardinals | OL Nick Kaczur |
| 4.3 | San Francisco 49ers | RB Darren Sproles |
| 4.4 | Pittsburgh Steelers | OL David Baas |
| 4.5 | Cleveland Browns | DB Kelvin Hayden |
| 4.6 | Dallas Cowboys (thru WAS.) | TE Bo Scaife |
| 4.7 | Dallas Cowboys | WR Chris Henry |
| 4.8 | Buffalo Bills | RB Maurice Clarett |
| 4.9 | Dallas Cowboys (thru K.C.) | DB James Butler |
| 4.10 | Philadelphia Eagles | OL Chris Myers |
| 4.11 | Dallas Cowboys (thru RAI.) | DL Luis Castillo |
| 4.12 | Denver Broncos | TE Kevin Everett |
| 4.13 | Dallas Cowboys (thru S.D.) | QB Ryan Fitzpatrick |
| 4.14 | New Orleans Saints | LB Leroy Hill |
| 4.15 | Cincinnati Bengals | WR Matt Jones |
| 4.16 | New York Jets | OL Khalif Barnes |
| 4.17 | Detroit Lions (thru RAI. thru DET.) | DB Fabian Washington |
| 4.18 | Detroit Lions (thru RAI. thru GIA.) | RB Samkon Gado |
| 4.19 | Tennessee Titans (thru SEA.) | OL Chris Kemoeatu |
| 4.20 | Tennessee Titans | TE Alex Smith |
| 5.1 | Miami Dolphins | DB Ron Bartell |
| 5.2 | Arizona Cardinals | K Mike Nugent |
| 5.3 | Dallas Cowboys (thru S.F.) | DB Josh Bullocks |
| 5.4 | Pittsburgh Steelers | DL Mike Patterson |
| 5.5 | Cleveland Browns | DL Jonathan Babineaux |
| 5.6 | Washington Redskins | WR Mike Williams |
| 5.7 | Dallas Cowboys | OL Richie Incognito |
| 5.8 | Buffalo Bills | OL Ray Willis |
| 5.9 | San Diego Chargers (thru DAL. thru K.C.) | OL Adam Snyder |
| 5.10 | Philadelphia Eagles | OL Evan Mathis |
| 5.11 | Los Angeles Raiders | QB Charlie Frye |
| 5.12 | Denver Broncos | OL Geoff Hangartner |
| 5.13 | San Diego Chargers | DL Matt Roth |
| 5.14 | New Orleans Saints | RB Madison Hedgecock |
| 5.15 | Cincinnati Bengals | LB David Pollack |
| 5.16 | New York Jets | WR Reggie Brown |
| 5.17 | Detroit Lions | DB Stanford Routt |
| 5.18 | Detroit Lions (thru GIA.) | OL Trai Essex |
| 5.19 | Seattle Seahawks | WR Roydell Williams |
| 5.20 | Pittsburgh Steelers (thru thru TEN.) | DL Marcus Spears |
season 35
- Week 19:
DET. 14
-
Harrison GearstR
RB - Buffalo
-
Jeremy MaroneyP
RB - New York
-
Matt MooreR
RB - Cleveland -
Rodney JohnsonR
RB - Cleveland -
Vance McDonaldR
TE - Baltimore -
D.D. ChaneyR
RB - Philadelphia -
Quincy JohnsonR
RB - Los Angeles
Legend:
D = Return Doubtful
Q = Return Questionable
P = Return Probable
R = Returned, Currently Available-
